Jan 01, 2014  Edward C. Chao, DO, is an associate clinical professor of medicine at the University of California, San Diego, and VA Healthcare System, San Diego. Note of disclosure: Dr. Chao serves as a member of the advisory board for Janssen Pharmaceuticals, which manufactures an SGLT-2 inhibitor for the treatment of diabetes.

Journal List; Int J Diabetes Dev Ctries; International Journal of Diabetes in Developing Countries Vols. 28 to 30; 2008 to 2010; Vol. Articles from International Journal of Diabetes in Developing Countries. Apr 19, 2017 Int J Diabetes Dev Ctries 1995; 15: 64–67. Google Scholar; 78. Agarwal AK, Singh M, Arya V, Garg U, Singh VP, Jain V. Prevalence of peripheral arterial disease in type 2 diabetes mellitus. Oct 30, 2018  The global prevalence of diabetes. among adults over 18 years of age has risen from 4.7% in 1980 to 8.5% in 2014 (1). Diabetes prevalence has been rising more rapidly in middle- and low-income countries. Both diabetes and psychiatric disorders are common, and it is also known that each condition may worsen the other. Since they also frequently coexist, it is important to recognize the adverse impacts that each has on the other in order that both these conditions can be managed effectively and successfully. Apr 01, 2005  Evidence suggests that stressful experiences might affect diabetes, in terms of both its onset and its exacerbation. In this article, the authors review some of this evidence and consider ways in which stress might affect diabetes.

International Journal of Diabetes in Developing Countries Vols. 28 to 30; 2008 to 2010
Vol. 30 2010	v.30(1): 1–56 Jan-Mar 2010 v.30(2): 63–108 Apr-Jun 2010
Vol. 29 2009	v.29(1): 1–42 Jan-Mar 2009 v.29(2): 49–101 Apr-Jun 2009 v.29(3): 103–142 Jul-Aug 2009 v.29(4): 143–177 Oct-Dec 2009
Vol. 28 2008	v.28(1): 1–31 Jan-Mar 2008 v.28(2): 32–68 Apr-Jun 2008 v.28(3): 71–100 Jul-Sep 2008 v.28(4): 101–134 Oct-Dec 2008

Also found in: Dictionary, Thesaurus, Medical, Legal, Financial, Acronyms, Wikipedia.

diabetes mellitus

[‚dī·ə′bēd·ēz ′mel·ə·dəs] (medicine)

Diabetes Mellitus

a chronic disease characterized by all kinds of metabolic disorders, chiefly carbohydrate, caused by the absolute or (more often) relative deficiency of the pancreatic hormone, insulin.

Heredity plays a major role in the origin of functional insufficiency of the islands of Langerhans of the pancreas, which produce insulin; the functional insufficiency may result from a trauma, inflammation, sclereosis of the pancreatic vessels, infections, intoxication, psychological trauma, excessive consumption of carbohydrates, and overeating in general. The functional condition of the other endocrine glands—the pituitary, adrenals, thyroid, and so forth—and the central and autonomic nervous systems is another factor. Because of the insulin deficiency the liver and muscles become unable to convert sugar into glycogen, and all the tissues lose their capacity to oxidize sugar and use it as an energy source. Moreover, glyconeogenesis also takes place —that is, sugar is formed from proteins and fats. As a result, sugar accumulates in the blood—to as much as 0.2-0.4 g per 100 milliliters of blood or more (hyperglycemia). When the amount of sugar in the blood is more than 0.18 g (“kidney threshold”), some of the sugar in the renal tubules is not reabsorbed and is excreted in the urine (glycosuria).

In more severe cases, liver function weakens, glycogen ceases to be synthesized and accumulates, and the products of protein and fat decomposition are no longer rendered harmless. As a result, a substantial quantity of ketone bodies, especially acetoacetic and /3- hydroxybutyric acids appear in the blood and then in the urine. The accumulation of these acids disturbs the acid-base equilibrium, causing acidosis. /auto-tune-81-mac-crack.html. Acidosis may result in a diabetic coma.

Diabetes mellitus patients suffer from an intensified appetite and thirst (hunger and thirst may not be very intense in mild cases), increased excretion of urine (up to 5–8 liters a day) with a high specific gravity, itching of the skin and external genitalia, inflammation of the oral mucosa, pain along the nerve trunks (polyneuritis), and muscular and sexual weakness. The menstrual cycle is disturbed in women; spontaneous abortions or stillbirths may occur in pregnant women. Precision tune auto 8 mile. The blood cholesterol level rises in diabetics, promoting the early onset of atherosclerosis, which is often combined with hypertonia. Marked changes in the cardiovascular system, kidneys, and eyes are among the serious complications of diabetes mellitus.

Treatment is individualized, taking into account the specific metabolic disorder. In mild forms, a special diet is prescribed, taking into account individual energy expenditures, and exercise therapy (especially for obese persons); in some cases, sugar-reducing sulfanilamide preparations (which are particularly effective in elderly persons with a tendency toward obesity) are prescribed. In moderate and severe forms insulin therapy is undertaken; long-acting insulin preparations with a sugar-reducing action are used to prolong the action of insulin.

Int J Diabetes Dev C Code

Want to thank TFD for its existence? Tell a friend about us, add a link to this page, or visit the webmaster's page for free fun content.
Link to this page:

Int J Dev Neurosci

<a href='https://encyclopedia2.thefreedictionary.com/Diabetes+Mellitus'>Diabetes Mellitus</a>

Int J Diabetes Dev Ctries